Table 4.
Main Results of the Economic Analysis
|
Group A |
Group B |
Differences |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Cost (€) | Survival (LY) | QALYs | Cost (€) | Survival (LY) | QALYs | Cost (€) | Survival (LY) | QALYs | |
| Without Correction for Censoring | |||||||||
| Mean | 1,008 | 2.91 | 2.40 | 3,697 | 3.16 | 2.65 | 2,689 | 0.25 | 0.25 |
| SD | 118 | 0.10 | 0.08 | 1,077 | 0.29 | 0.25 | 1,083 | 0.31 | 0.26 |
| UCI | 1,246 | 3.10 | 2.56 | 6,007 | 3.76 | 3.14 | 4,998 | 0.89 | 0.79 |
| LCI | 786 | 2.72 | 2.24 | 1,811 | 2.60 | 2.18 | 784 | −0.34 | −0.26 |
| Min | 659 | 2.55 | 2.10 | 789 | 2.10 | 1.76 | −356 | −0.81 | −0.66 |
| Max | 1,587 | 3.26 | 2.70 | 8,278 | 4.35 | 3.64 | 7,413 | 1.47 | 1.25 |
| With Correction for Censoring | |||||||||
| Mean | 1,383 | 4.99 | 4.18 | 4,661 | 3.62 | 3.02 | 3,278 | −1.37 | −1.16 |
| SD | 334 | 0.73 | 0.61 | 2,268 | 0.70 | 0.59 | 2,297 | 1.02 | 0.86 |
| UCI | 2,077 | 6.62 | 5.55 | 9,596 | 5.07 | 4.25 | 8,277 | 0.55 | 0.46 |
| LCI | 771 | 3.77 | 3.16 | 1,052 | 2.31 | 1.94 | −442 | −3.46 | −2.90 |
| Min | 459 | 3.20 | 2.68 | 95 | 1.14 | 0.96 | −1,594 | −5.34 | −4.48 |
| Max | 2,774 | 8.62 | 7.24 | 17,382 | 6.39 | 5.35 | 15,864 | 4.16 | 3.49 |
Abbreviations: LY, life years; SD, standard deviation; LCI, lower confidence interval; UCI, upper confidence interval. Results were based on 5,000 non-parametric bootstrap experiments; cost measured in EUR; effectiveness evaluated at life years; survival analysis with correction for censoring was based on Kaplan-Meier estimator via inverse probability weights for uncensored subjects.