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. 2019 Mar 29;43:576–586. doi: 10.1016/j.ebiom.2019.03.072

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© 2019 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 2 — Manhattan plots of epigenome-wide association results for FEV₁ (forced expired volume in 1 s), FVC (forced vital capacity; bottom), FEV₁/FVC and COPD (chronic obstructive pulmonary disease) from the discovery Generation Scotland: Scottish Family health study cohort data. The red line correspond to the genome-wide (p = 3.6 × 10⁻⁸) and suggestive (p = 1.0 × 10⁻⁵) significance level. Labels are for the nearest gene to genome-wide significant CpG sites. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)