Table 4.
Key nodes in stage LIN networks based on Degree and Betweenness centrality measures.
| Gene name | Gene type | DNR-LIN network* | PPR-LIN network* | Some related cancers | Reference (PMID) |
|---|---|---|---|---|---|
| hsa_circ_0000591 | circRNA | D, B | D, B | — | — |
| CCNT2 | Protein coding | D, B | — | Leukemia | 28409330 |
| hsa_circ_0000592 | circRNA | D | D, B | — | — |
| NRAS | Protein coding | D, B | D, B | Bladder, Colorectal, Melanoma |
21072204 22820081 28074351 |
| WEE1 | Protein coding | D, B | D, B | Breast, Leukemia, Melanoma, Brain | 27427153 |
| CCNG1 | Protein coding | D, B | — | Bladder, Ovarian |
27982046 25981880 |
| hsa_circ_0001741 | circRNA | D | D | — | — |
| hsa_circ_0017586 | circRNA | D | D | — | — |
| hsa_circ_0007646 | circRNA | D | D | Hypopharyngeal squamous cell carcinoma, Pancreatic |
28514762 29922161 |
| hsa_circ_0003221 | circRNA | D | D | Bladder | 29125888 |
| MDM2 | Protein coding | B | B | Bladder, Ovarian |
28498468 28817834 |
| PWAR6 | lncRNA | B | B | Glioma, Breast |
30472640 30297886 |
| KCNQ1OT1 | lncRNA | B | B | Breast, Lung |
30157476 28600629 |
| hsa_circ_0008345 | circRNA | — | D | — | — |
| AC015813.1 | lncRNA | B | B | — | — |
| IGF1R | Protein coding | B | — | Bladder, Colon |
27470393 28882129 |
| NEAT1 | lncRNA | — | B | Bladder, thyroid |
30349370 30596336 |
| GABPB1-AS1 | lncRNA | — | B | — | — |
| hsa_circ_0011536 | circRNA | — | D | — | — |
*D: Degree, B: Betweenness.