Table 5.
Key nodes in stage GIN networks based on Degree and Betweenness centrality measures.
| Gene name | Gene type | DNR-GIN network* | PPR-GIN network* | Some related cancers | Reference (PMID) |
|---|---|---|---|---|---|
| FADD | Protein coding | D, B | — | Pancreatic, Lung |
28454341 30190126 |
| PSMC4 | D | D | Breast | 18042273 | |
| GAPDHP1 | Pseudogene | D, B | D | — | — |
| PDIA5 | Protein coding | D | — | Melanoma | 25912252 |
| SLC25A1 | Protein coding | D | — | Lung | 29651165 |
| TFRC | Protein coding | D | D | Melanoma | 28551638 |
| SNRPA | Protein coding | D | — | Gastric | 30039889 |
| MYC | Protein coding | D, B | D, B | Bladder, Prostate |
29463565 27159573 |
| MCM3 | Protein coding | D | D | Hepatocellular Carcinoma | 30363964 |
| HSPA1A | Protein coding | D | Bladder, Ovarian |
23874968 26868087 |
|
| NR3C1 | Protein coding | B | — | Bladder, Gastric |
29991691 29285253 |
| NUP214 | Protein coding | B | — | Leukemia | 25120641 |
| NR2F1-AS1 | lncRNA | B | B | Hepatocellular carcinoma | 29602203 |
| GLI2 | Protein coding | B | — | Bladder, Gastric |
27465044 28975979 |
| NCOR2 | Protein coding | B | — | Lung | 29764865 |
| ADCY7 | Protein coding | B | B | Leukemia | 26220344 |
| FASN | Protein coding | — | D, B | Bladder, Breast |
30221356 28922023 |
| CBX2 | Protein coding | — | D | Ovarian | 30478317 |
| CDC25B | Protein coding | — | D, B | Bladder, Endometrial, Gastric |
29234286 29353204 27863420 |
| ADCY3 | Protein coding | — | D | Gastric | 24113161 |
| DAG1 | Protein coding | — | D | Leukemia | 28591567 |
| STAT1 | Protein coding | — | B | Bladder, Breast, Lung, Melanoma, Gastric, Colorectal, Esophageal |
27080594 28950072 |
| ANXA2P2 | Pseudogene | — | B | — | — |
| CDK6 | Protein coding | — | B | Bladder, Esophageal |
30362519 30551480 |
| IL10 | Protein coding | — | B | Bladder, Melanoma, Lung |
27987237 26188281 |
| PART1 | lncRNA | B | — | Esophageal, Lung, Prostate |
30049286 28819376 29261512 |
| LINC02607 | lncRNA | — | B | — | — |
*D: Degree, B: Betweenness.