Table 3.

Comparison of inflammatory anemia-associated parameters and creatinine levels of patients with sepsis in survivor and non-survivor groups

	After ICU admission
	Day 1	Day 3	Day 7
Hemoglobin (g/L)
Survivor	125 (103–163)	106 (90–180)	95 (81–160)
Non-survivor	123 (100–161)	99 (78–155)	95 (80–112)
RDW (%)
Survivor	13.3 (11.5–19.0)	14.0 (11.9–19.8)	13.9 (11.9–18.7)
Non-survivor	14.2 (11.8–19.9)	15.4 (12.2–20.1)a	15.3 (12.5–20.4)a
EPO (IU/L)
Survivor	93.8 (49.6–428.4)	44.7 (20.0–278.7)b	20.7 (10.9–130.5)b
Non-survivor	51.3 (20.8–126.2)a	23.1 (12.1–81.4)ab	11.1 (8.1–29.4)ab
sTfR (nmol/L)
Survivor	20.2 (13.5–27.9)	20.4 (13.5–27.8)	21.7 (13.7–27.9)
Non-survivor	20.7 (13.4–28.0)	20.5 (13.6–28.1)	19.6 (13.4–27.4)
Hepcidin (ng/mL)
Survivor	133.9 (60.2–185.5)	66.3 (24.8–95.3)b	45.7 (20.4–69.3)b
Non-survivor	172.2 (110.1–231.5)a	99.8 (45.9–122.4)ab	65.6 (35.2–99.7)ab
Iron (µmol/L)
Survivor	8.1 (2.3–12.5)	8.6 (2.4–15.4)	10.6 (3.3–19.4)
Non-survivor	7.6 (2.3–15.7)	6.3 (2.9–8.2)a	6.6 (3.0–11.4)a
Ferritin (ng/mL)
Survivor	172.5 (85.2–237.1)	555.0 (340.1–615.8)b	276.7 (99.5–524.6)b
Non-survivor	227.1 (110.7–302.8)a	581.9 (423.9–702.4)ab	322.5 (218.6–364.6)a
IL–6 (pg/mL)
Survivor	34.2 (15.7–55.5)	23.3 (8.6–45.3)b	21.9 (11.7–89.0)b
Non-survivor	124.3 (49.3–171.9)a	76.0 (29.0–153.6)ab	44.9 (10.2–107.2)ab
sTfR/log ferritin
Survivor	9.0 (6.1–12.5)	7.5 (4.9–10.4)	9.3 (5.5–13.2)
Non-survivor	8.8 (5.7–11.9)	6.3 (4.9–10.3)a	7.9 (5.4–11.0)a
Creatinine (µmol/L)
Survivor	119 (56–188)	132 (114–201)	124 (67–196)
Non-survivor	138 (65–198)a	176 (114–235)ab	217 (115–311)ab

Values are the mean ± standard deviation or median (range)

EPO erythropoietin; IL-6 interleukin-6; RDW red blood cell distribution width; sTfR soluble transferrin receptor

^aP < 0.05 vs. survivor

^bP < 0.05 vs. day 1 of ICU admission