Table 2.
Comparison of the mRNA expression of semaphorins in peripheral blood samples from healthy individuals and CLL patients.
| Semaphorins | CLL patients | Healthy control group |
|||
|---|---|---|---|---|---|
| Stage I | Stage II |
Total | P value | ||
| SEMA3A expression† |
4.49 ± 1.61 |
11.12 ± 5.35 |
7.58 ± 2.66 |
1.01 ± 0.31 |
*= 0.05 **=0.01 ***=0.001 |
| SEMA4A expression† |
1.87 ± 0.72 |
1.26 ± 0.47 |
1.59 ± 0.44 |
1.00 ± 0.14 |
*=0.48 **=0.25 ***=0.61 |
| SEMA4D expression† |
2.96 ± 0.72 |
3.48 ± 2.02 |
3.20 ± 0.99 |
1.00 ± 0.27 |
*=0.49 **=0.01 ***=0.01 |
The *, ** and *** represent the difference of the fold change expression of a specified semaphorin between stage I and stage II patients, between stage I patients and control group, and between stage II patients and control group, respectively.
†
The amounts of the semaphprin expression were assessed as fold change and expressed as mean ± SEM.