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. 2019 Jun 4;10:1264. doi: 10.3389/fimmu.2019.01264

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Copyright © 2019 Pereira, Pérez-Cabezas, Ribeiro, Maia, Cardoso, Dias, Azevedo, Ferreira, Garcia, Rodrigues, Castro-Chaves, Martins, Aguiar, Pineda, Amraoui, Fecarotta, Leão-Teles, Deng, Savage and Macedo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CD1d-restricted lipid antigen presentation by monocytes from Fabry and Gaucher disease patients. Monocytes from Fabry (A) and Gaucher (B) disease patients and control subjects were loaded with graded doses of α-GalCer (Fabry and Gaucher) or α-Gal-(1-2)-α-GalCer (Gaucher) and co-cultured with an iNKT cell line. Patients are represented with filled symbols and control subjects with open symbols. Each symbol represents mean ± SD of duplicates for the same individual at the indicated antigen concentration.