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MRD detection methods. MRD, minimal residual disease; CSC, cancer stem cell; CTC, circulating tumor cell; DTC, disseminating tumor cell; ctDNA, circulating tumor DNA; PB, peripheral blood; PBSC, peripheral blood stem cell; BM, bone marrow; IC, immunocytology; FCM, flow cytometry; PCR, polymerase chain reaction; aCGH, array comparative genomic hybridization; MPS, massively paralleled sequencing; RT-PCR, reverse transcriptase-PCR.
