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. 2019 Jun 4;10:1267. doi: 10.3389/fimmu.2019.01267

Figure 1.

Figure 1

The chemical structure of benznidazole (Bzl) used in this study is shown (A). Cardiomyocytes were treated with 15 μM of Bzl for 30 min and then with 10 mg/L LPS for 24 h. SOCS3 mRNA levels were analyzed by RT-qPCR and normalized against 18S rRNA (B). Results are expressed as the mean of three independent experiments (n = 3, 5 replicates/treatment) ± SEM. White bar: Unstimulated control cells. Black bar: LPS stimulated cells. Gray bar: LPS stimulated and Bzl treated cells **P < 0.001, vs. LPS-stimulated cells; ##P < 0.001 vs. control cells.