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. 2019 Jun 4;10:1261. doi: 10.3389/fimmu.2019.01261

Figure 2.

Figure 2

Increased proportion of CD27-CD11b+ NK cells at day 2 post-infection. WT mice were infected with HSV-2 ivag and vaginal cells were isolated at baseline through to day 3 post-infection. Vaginal cells were stained for CD45, CD3, NK1.1 CD27, and CD11b. Cells were first gated on CD45+, CD3–, and NK1.1+ to determine the NK cell population. NK cells were then examined for CD27 and CD11b expression. Representative flow plots are shown in (A). Proportion of double-negative NK cells (CD27–CD11b–; Q4) is shown in (B; n = 4). Proportion of CD27+ (CD27+CD11b–; Q1) NK cells is shown in (C; n = 4). Proportion of double-positive (CD27+CD11b+; Q2) NK cells is shown in (D; n = 3). Proportion of CD11b+ (CD27–CD11b+; Q3) NK cells is shown in (E; n = 4). *p < 0.05; **p < 0.01; ***p < 0.001.