Table 1.
M. tb genes with extreme patterns of variation across multiple patients and multiple measures.
| Gene | lm | z-score | Z0 | FST |
|---|---|---|---|---|
| Rv2020c (hypothetical) | 13 | 0 | 0 | 6 |
| Rv1318c | 11 | 0 | 0 | 11 |
| Rv1319c | 9 | 0 | 0 | 6 |
| Rv3109 (moaA1) | 11 | 0 | 0 | 8 |
| Rv 1267c (embR) | 10 | 0 | 0 | 5 |
| Rv2351c (plcA) | 5 | 0 | 0 | 5 |
| Rv2350c (plcB) | 5 | 0 | 0 | 4 |
| Rv2082 (hypothetical) | 3 | 0 | 0 | 3 |
| Rv2081c (conserved transmembrane protein) | 2 | 0 | 0 | 2 |
| Rv3051c (nrdE) | 4 | 6 | 2 | 7 |
| Rv0338c | 2 | 1 | 0 | 2 |
| Rv0684 (fusA1) | 2 | 1 | 2 | 3 |
| Rv1164 (narI) | 2 | 1 | 2 | 5 |
| Rv1327c (glgE) | 2 | 1 | 0 | 2 |
| Rv1630 (rpsA) | 2 | 2 | 1 | 2 |
| Rv0667 (rpoB) | 2 | 3 | 1 | 4 |
| Rv0668 (rpoC) | 1 | 1 | 2 | 4 |
The number of patients in whom each gene was identified as an outlier is shown for linear regression of diversity in sputum versus culture (lm), fold change in diversity (z-score) or absolute difference (Z0) and FST analyses.