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. 2019 Jun 4;10:1236. doi: 10.3389/fimmu.2019.01236

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Copyright © 2019 Collmann, Pijnenburg, Hamzei-Taj, Minassian, Folz-Donahue, Kukat, Aswendt and Hoehn.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Timeline summarizing in vivo and ex vivo investigations after LV-iNOS/Ym1-IR injections. BLI signal intensities were repeatedly recorded before stroke induction (MCAO), and at highlighted time points of the respective study group after MCAO (LV-iNOS-IR mice in red, LV-Ym1-IR mice in blue). MRI was conducted 1 week post stroke. Brains were prepared for IHC and RNA-ISH at 14 dps (LV-iNOS-IR mice) or at 21 dps (LV-Ym1-IR mice). BLI, Bioluminescence Imaging; dps, days post stroke; IR, imaging reporter (Luc2-T2A-eGFP); RNA-ISH, RNA in situ hybridization.