Table 1.

Glossary of the main technical parameters.

Parameter	Abbreviation	Units	Meaning
Hazard ratio	HR	Adimensional	The event risk in the comparison between the experimental group and the control group
Mean survival time	MST	Time	The survival estimate per patient from time 0 to infinity; MST is calculated from the area under the survival curve, using a model-based estimation method (e.g., proportional hazard model, models of Weibull, Gomperz, etc.)
Restricted mean survival time	RMST	Time	The survival estimate per patient calculated from time 0 to a pre-determined time-point in the follow-up; calculations are the same as those employed for MST
Mean lifetime survival	MLS	Time	Synonymous for MST
Area under the survival curve	AUC	Time	The same as MST, but has a model independent nature because of its estimation according to the trapezoidal rule
Restricted area under the survival curve	rAUC	Time	The same as AUC, but is calculated from time 0 to a pre-determined time-point
Milestone survival	–	Percentage (from 0 to 100%) or rate (from 0 to 1)	The survival value calculated at a predetermined time-point according to the Kaplan-Meier curve