Table 1. Details of gene-disease pairs currently analysed by CardioClassifier.
The disease class column details the larger sub-panels relating to broad disorder types that each disease and gene set are within.
| Disease | Disease Class | Genes | Total Genes |
|---|---|---|---|
| DCM | Cardiomyopathy | LMNA, TNNT2, SCN5A, TTN, TCAP, MYH7, VCL, TPM1, TNNC1, RBM20, DSP, BAG3 | 12 |
| HCM | Cardiomyopathy | MYH7, TNNT2, TPM1, MYBPC3, PRKAG2, TNNI3, MYL3, MYL2, ACTC1, CSRP3, PLN, TNNC1, GLA, FHL1, LAMP2, GAA | 16 |
| ARVD/C | Cardiomyopathy | DSP, PKP2, DSG2, DSC2, JUP | 5 |
| RCM | Cardiomyopathy | TNNI3 | 1 |
| ncCM | Cardiomyopathy | MYBPC3, MYH7 | 2 |
| Noonan syndrome | Cardiomyopathy | RAF1, SOS1, PTPN11, KRAS | 4 |
| Long QT syndrome | Arrhythmia | KCNQ1, KCNH2, SCN5A, KCNE1, KCNE2 | 5 |
| Brugada syndrome | Arrhythmia | SCN5A | 1 |
| CPVT | Arrhythmia | RYR2 | 1 |
| Marfan syndrome | Aortopathy | FBN1 | 1 |
| FH | - | LDLR | 1 |