Table 1. Diagnostic groups, demographics and sleep parameters of the cohort.
| Diagnosis | |||||
|---|---|---|---|---|---|
| All (n = 126) | NT1 (n = 70) | NT2 (n = 47) | IH (n = 9) | P-value | |
| Demographics | |||||
| Gender (male/female) | 47/79 | 28/42 | 16/31 | 3/6 | 0.782* |
| Age (years) | 37.9 ± 13.1 | 38.3 ± 13.9 | 38. ± 12.4 | 33.4 ± 9.1 | 0.687 |
| BMI (kg m2) | 29.3 ± 7.3 | 30.4 ± 7.5 | 27.9 ± 7.1 | 26.0 ± 4.6 | 0.135 |
| ESS | 17.5 ± 4.1 | 18.6 ± 3.5 | 16.2 ± 4.4 | 16.2 ± 4.7 | 0.021† |
| Sleep parameters | |||||
| TST (min) | 387.4 ± 72.5 | 373.8 ± 73.8 | 406.4 ± 69.5 | 393.8 ± 28.1 | 0.223 |
| Sleep efficiency (%) | 82.3 ± 14.5 | 78.6 ± 16.3 | 87.1 ± 10.2 | 87.8 ± 4.4 | 0.002† |
| Sleep onset (min) | 10.3 ± 20.5 | 10.6 ± 24.6 | 9.5 ± 13.6 | 16.0 ± 3.0 | 0.106 |
| REM latency (min) | 62.0 ± 61.9 | 59.8 ± 66.9 | 62.8 ± 55.9 | 74.0 ± 57.0 | 0.486 |
| AHI | 3.4 ± 6.1 | 3.4 ± 5.4 | 3.6 ± 7.3 | 0.8 ± 1.0 | 0.711 |
| PLMI | 15.5 ± 29.3 | 18.7 ± 34.6 | 9.92 ± 17.9 | 3.3 ± 5.0 | 0.678 |
| REM duration (min) | 79.9 ± 35.4 | 75.3 ± 34.7 | 86.5 ± 36.5 | 78.5 ± 28.1 | 0.571 |
| N1 (% of TST) | 7.1 ± 4.2 | 8.4 ± 4.4 | 5.5 ± 3.2 | 4.93 ± 1.7 | 0.001† |
| N2% | 36.4 ± 10.4 | 35.1 ± 10.0 | 37.9 ± 10.5 | 41.3 ± 15.4 | 0.302 |
| M3% | 23.3 ± 8.6 | 21.4 ± 8.4 | 25.6 ± 8.3 | 26.6 ± 11.2 | 0.078 |
| REM% | 17.5 ± 6.8 | 16.5 ± 7.2 | 18.8 ± 6.1 | 18.0 ± 5.8 | 0.311 |
| Arousal index | 20.1 ± 11.8 | 21.8 ± 13.2 | 17.7 ± 9.5 | 20.2 ± 1.0 | 0.252 |
| MSL (min) | 4.2 ± 3.1 | 3.5 ± 2.9 | 4.2 ± 2.5 | 8.4 ± 4.7 | 0.001† |
NT1, narcolepsy type 1; NT2, narcolepsy type 2; IH, idiopathic hypersomnia; BMI, body mass index; ESS, Epworth Sleepiness Score; REM; rapid eye movement; AHI, apnea–hypopnea index; PLMI, Periodic Limb Movement Index; N1, Stage 1 sleep; N2, Stage 2 sleep; N3, Stage 3 sleep; TST, total sleep time; MSL, mean sleep latency.
*
Analysis was performed using chi-square test for the diagnostic categories.
†
Post-hoc test showed significant difference between diagnostic categories: ESS of NT1 versus NT2, P = 0.021; sleep efficiency (%) of NT1 versus NT2, P = 0.002; N1 (% of TST) of NT1 versus NT2, P = 0.001; MSL of NT1 versus IH, P = 0.001; MSL of NT2 versus IH, P = 0.024.