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. 2019 May 29;10:1166. doi: 10.3389/fimmu.2019.01166

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Copyright © 2019 Blois, Dveksler, Vasta, Freitag, Blanchard and Barrientos.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Summary of galectins' glycan specificity, functions and sources of expression in mammalian pregnancies. Question marks (?) denote putative functions (not yet experimentally confirmed in the context of pregnancy). BG, blood group; uNK, uterine natural killer; ICM, inner cell mass; VT, villous cytotrophoblast; EVT, extravillous trophoblast; Syn, syncytiotrophoblast; GDM, gestational diabetes mellitus; SA, spontaneous abortion; PE, preeclampsia; HELLP, hemolysis elevated liver enzymes and low platelet syndrome; GTD, gestational trophoblastic disease; IUGR, intrauterine growth restriction. ↑ and ↓ denote increased/peak and decreased expression, respectively. Mannose Galactose N-acetylglucosamine N-acetylgalactosamine Sialic Acid Fucose.

Inline graphic — Summary of galectins' glycan specificity, functions and sources of expression in mammalian pregnancies. Question marks (?) denote putative functions (not yet experimentally confirmed in the context of pregnancy). BG, blood group; uNK, uterine natural killer; ICM, inner cell mass; VT, villous cytotrophoblast; EVT, extravillous trophoblast; Syn, syncytiotrophoblast; GDM, gestational diabetes mellitus; SA, spontaneous abortion; PE, preeclampsia; HELLP, hemolysis elevated liver enzymes and low platelet syndrome; GTD, gestational trophoblastic disease; IUGR, intrauterine growth restriction. ↑ and ↓ denote increased/peak and decreased expression, respectively. Mannose Galactose N-acetylglucosamine N-acetylgalactosamine Sialic Acid Fucose.