Figure 6.
Adoptive transfer of mincle stimulated DCs restricts Mtb survival in Abx treated mice. Lung DCs (5 × 106) from Mtb infected mice were PPD pulsed and stimulated with TDB (20 μg/ml) overnight. Cells were adoptively transferred to Abx treated mice, 24 h prior to Mtb infection. After 3 wk, Mtb burden was monitored in the lungs by CFU assay. Data represented as mean ± SD are of 2 independent experiments (n = 5 mice/group). **p < 0.01, ***p < 0.001.