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. 2019 May 29;10:1199. doi: 10.3389/fimmu.2019.01199

Figure 1.

Figure 1

Functional derangement of BMDMs in T-bet KO mice. (A) BMDMs were identified by flow cytometry and the purity of those growth was comparable between T-bet KO and WT mice. (B) Levels of IL-17, IL-23, INF-γ, and TNF-α were analyzed using flow cytometry in BMDMs from T-bet KO mice and WT mice after MSU crystal challenge in vitro. Results are representative of 3 independent experiments. Each group had 3–5 mice **P < 0.01. BMDM, bone marrow-derived macrophage; IFN, interferon; IL, interleukin; KO, knockout; MSU, monosodium urate; TNF, tumor necrosis factor; WT, wild type.