Table 4.
Multivariate survival analysis of the prognostic factors for all stage I and N0 gastric cancer patients
| Factors | Stage I (n = 396) | Stage T1‐4aN0 (n = 569) | ||||||
|---|---|---|---|---|---|---|---|---|
| Overall survival | Cancer specific survival | Overall survival | Cancer specific survival | |||||
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
| Age | ||||||||
| ≧60 y vs <60 y | 1.7 (0.9‐3.1) | 0.065 | 1.1 (0.5‐2.3) | 0.791 | 1.4 (0.9‐2.1) | 0.088 | 1.0 (0.6‐1.6) | 0.969 |
| Tumor size | ||||||||
| <5 cm vs ≧5 cm | 1.2 (0.6‐2.5) | 0.600 | 1.7 (0.7‐3.9) | 0.199 | 1.4 (0.9‐2.1) | 0.135 | 1.4 (0.9‐2.4) | 0.124 |
| AJCC stage | ||||||||
| IB vs IA | 2.2 (1.2‐4.1) | 0.008 | 4.5 (2.0‐9.9) | <0.001 | 2.2 (1.2‐4.0) | 0.009 | 4.2 (1.8‐9.5) | <0.001 |
| IIA vs IA | 3.0 (1.7‐5.4) | <0.001 | 6.4 (2.9‐14.1) | <0.001 | ||||
| IIB vs IA | 5.9 (3.3‐10.6) | <0.001 | 11.0 (5.0‐24.7) | <0.001 | ||||
| eLN | ||||||||
| <16 vs ≧16 | 2.2 (1.2‐4.1) | 0.008 | 2.6 (1.2‐5.6) | 0.012 | 1.6 (0.9‐2.4) | 0.054 | 1.7 (0.9‐2.9) | 0.063 |
| Anemia | ||||||||
| Yes vs no | 1.3 (0.6‐2.6) | 0.309 | 1.3 (0.5 −3.0) | 0.589 | 1.3 (0.8‐2.0) | 0.273 | 1.9 (1.1 −3.3) | 0.022 |
| PFC stage | ||||||||
| PFC1 vs PFC0 | 2.5 (1.4‐4.3) | 0.003 | 3.0 (1.4‐6.1) | 0.004 | 2.2 (1.5‐3.2) | <0.001 | 3.0 (1.9‐4.8) | 0.000 |
eLN, Number of examined lymph node; CI, confidence interval; HR, hazard ratio; PFC0, plasma fibrinogen concentration <4 g/L; PFC1, plasma fibrinogen concentration ≧4 g/L.