Table 5.
Multivariate survival analysis of the prognostic factors for stage I and N0 gastric cancer patients without adjuvant chemotherapy
| Factors | Stage I (n = 256) | Stage T1‐4aN0 (n = 325) | ||||||
|---|---|---|---|---|---|---|---|---|
| Overall survival | Cancer specific survival | Overall survival | Cancer specific survival | |||||
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
| Age | ||||||||
| ≧60 y vs <60 y | 2.5 (1.1‐5.6) | 0.032 | 1.6 (0.5‐5.4) | 0.441 | 1.4 (0.8‐2.5) | 0.191 | 1.0 (0.5‐1.9) | 0.929 |
| Tumor size | ||||||||
| <5 cm vs ≧5 cm | 0.7 (0.2‐2.2) | 0.503 | 1.2 (0.3‐4.4) | 0.816 | 1.0 (0.6‐1.8) | 0.956 | 1.1 (0.5‐2.4) | 0.741 |
| AJCC stage | ||||||||
| IB vs IA | 2.5 (1.1‐5.5) | 0.023 | 4.5 (2.0‐9.9) | <0.001 | 2.8 (1.3‐5.9) | 0.008 | 4.2 (1.5‐12.3) | 0.008 |
| IIA vs IA | 5.0 (2.4‐10.2) | <0.001 | 10.1 (3.8‐27.2) | <0.001 | ||||
| IIB vs IA | 15.8 (7.6‐33) | <0.001 | 27.6 (9.9‐75.6) | <0.001 | ||||
| eLN | ||||||||
| <16 vs ≧16 | 2.0 (0.9‐4.3) | 0.094 | 3.2 (1.1‐9.7) | 0.039 | 1.6 (0.9‐2.9) | 0.083 | 1.7 (0.8‐3.6) | 0.186 |
| Anemia | ||||||||
| Yes vs no | 1.3 (0.5‐3.9) | 0.591 | 0.9 (0.2 −3.5) | 0.840 | 2.1 (1.1‐4.0) | 0.025 | 3.3 (1.4 −8.0) | 0.008 |
| PFC stage | ||||||||
| PFC1 vs PFC0 | 3.2 (1.5‐6.9) | 0.003 | 4.6 (1.5‐14) | 0.004 | 2.4 (1.4‐4.1) | 0.001 | 3.2 (1.6‐6.4) | 0.001 |
eLN, Number of examined lymph node; CI, confidence interval; HR, hazard ratio; PFC0, plasma fibrinogen concentration <4g/L; PFC1, plasma fibrinogen concentration ≧4g/L.