Figure 2. SN down-regulated cleavage of caspase-12 and caspase-3 in OGD injured PC12 cells: (A) immunoblotting images of cleaved caspase-12, procaspase-12, cleaved caspase-3, and procaspase-3 in different experimental conditions; (B) and (C), respectively, quantitative densitometric analysis of cleaved caspase-12/procaspase-12 and cleaved caspase-3/procaspase-3 ratios. Data are shown as means ± SEM (n=3): ^***p<0.001 vs. NC; ^###p<0.01 vs. OGD [NC: normal control; OGD: oxygen and glucose deprivation (4 h); OGD-SN: oxygen and glucose deprivation (4 h) co-treated with SN (100 µm); SN: sodium nitrite (100 µm) treated].