Table 7.
Frequencies of elevated marker levels in CS1 patients in relation to treatment.
| Seminoma | Nonseminoma | ||||||
|---|---|---|---|---|---|---|---|
| bHCG elevated | LDH elevated | bHCG elevated | AFP elevated | LDH elevated | |||
| n | n (%) | n (%) | n | n (%) | n (%) | n (%) | |
| 95% CI [%] | 95% CI [%] | 95% CI [%] | 95% CI [%] | 95% CI [%] | |||
| Before orchiectomy | 201 | 49 (24.4%) | 46 (22.9%) | 80 | 37 (46.3%) | 50 (62.5%) | 18 (22.5%) |
| 18.7 - 31.0 | 17.4 - 29.4 | 35.2 - 57.7 | 50.9 - 72.9 | 14.2 - 33.5 | |||
| postoperatively | 201 | 15 (7.5%) | 33 (16.4%) | 80 | 15 (18.8%) | 39 (48.8%) | 6 (7.5%) |
| 4.4 - 12.2 | 11.7 - 22.4 | 11.2 - 29.4 | 37.5 - 60.1 | 3.1 - 16.2 | |||
| p-valuea | <.0001 | 0.0280 | <.0001 | 0.0009 | 0.0027 | ||
| At completion of adjuvant therapy | 201 | 2 (1.0%) | 22 (10.9%) | 80 | 1 (1.3%) | 1 (1.3%) | 10 (12.5%) |
| 0.2 - 3.9 | 7.1 - 16.3 | 0.1 - 7.7 | 0.1 - 7.7 | 6.5 - 22.2 | |||
| p-valuea | <.0001 | 0.0004 | <.0001 | <.0001 | 0.0736 | ||
aMcNemar Test for comparisons of expression rates with rate before orchiectomy.