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Most indications are similar to that of OLT. Metabolic conditions have had the best documented support.
| Clinical indications for HCT |
|---|
| Congenital metabolic |
| Crigler-Najjar |
| Familial hypercholesterolemia |
| Alpha-1 antitrypsin deficiency |
| Glycogen storage disease |
| Urea cycle disorders |
| Factor VII deficiency |
| Acute Liver Failure |
| Drug induced |
| Alcoholic hepatitis |
| Viral hepatitis |
| Poisoning |
| Post resection failure |
| Mushroom poisoning |
| Idiopathic |
| Chronic liver failure |
