Table 1.

The characteristics of included studies

First author, year	Country	Ethnicity	Type of disease	Sample size	Genotype distribution		P-value for HWE	NOS score
					Cases	Controls
LEPR rs1137100					AA/AG/GG
Aijälä, 2014 [16]	Finland	Caucasian	CAD	151/877	66/75/10	361/398/118	0.617	7
An, 2016 [17]	China	East Asian	CAD	421/550	295/110/16	371/157/22	0.299	7
Roszkowska-Gancarz, 2014 [20]	Russia	Caucasian	MI	226/414	118/86/22	218/171/25	0.259	7
LEPR rs1137101					GG/GA/AA
Aijälä, 2014 [16]	Finland	Caucasian	CAD	152/882	48/80/24	312/427/143	0.878	7
An, 2016 [17]	China	East Asian	CAD	421/550	306/103/12	362/162/26	0.158	7
Khaki-Khatibi, 2018 [18]	Iran	South Asian	MI	80/80	18/37/25	30/36/14	0.576	8
Nowzari, 2018 [19]	Iran	South Asian	CAD	156/130	70/61/25	63/34/33	<0.001	7
Roszkowska-Gancarz, 2014 [20]	Russia	Caucasian	MI	226/414	59/108/59	116/206/92	0.976	7
Wu, 2013 [22]	China	East Asian	CAD	200/100	42/90/68	44/38/18	0.064	8
LEP rs7799039					GG/GA/AA
Nowzari, 2018 [19]	Iran	South Asian	CAD	156/130	61/73/22	58/51/21	0.095	7
Roszkowska-Gancarz, 2014 [20]	Russia	Caucasian	MI	226/414	67/120/39	139/203/72	0.885	7
Wang, 2013 [21]	China	East Asian	CAD	200/100	65/100/35	37/46/17	0.677	8
Zhai, 2013 [23]	China	East Asian	CAD	200/100	102/86/12	45/38/17	0.080	8
Zhao, 2006 [24]	China	East Asian	CAD	156/150	80/68/8	68/56/26	0.020	8
Zheng, 2014 [25]	China	East Asian	CAD	198/95	68/97/33	65/24/6	0.084	7

Abbreviation: MI, myocardial infarction.