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. 2019 Jun 10;39(6):BSR20181258. doi: 10.1042/BSR20181258

Figure 2. MiR-198 suppresses growth and promotes apoptosis in SGC-7901 cells.

Figure 2

(A) Cell proliferation was measured using CCK-8 assays. Overexpression of miR-198 inhibited SGC-7901 cell proliferation. (B,C) Colony formation ability was determined using colony formation assays. Overexpression of miR-198 inhibited the colony formation ability of SGC-7901 cells. (D,E) Cell-cycle distribution was detected using flow cytometry. (F) Apoptosis was detected using TUNEL staining assays. (G,H) Apoptosis was detected by Annexin-V FITC/PI double-staining, apoptotic cells were defined as Annexin V-positive/PI-negative, overexpression of miR-198 enhanced apoptosis induced by 5 μM cisplatin in SGC-7901 cells. *P<0.05; **P<0.01.