Table 4.

Adjusted diagnostic characteristics of the CAAD screen components

Diagnostic characteristics adjusted	Cognition	Anxiety	Apathy	Depression
AUC	0.80	0.81	0.79	0.85
Cut-off low risk	POI < 0.02	POI < 0.068	POI < 0.090	POI < 0.035
Sensitivity	93%	95%	94%	94%
Specificity	55%	39%	62%	41%
Cut-off high risk	POI > 0.30	POI > 0.76	POI > 0.43	POI > 0.57
Sensitivity	27%	5%	13%	50%
Specificity	97%	99%	97%	99%
Low risk: n (%)	55 (43%)	42 (33%)	69 (55%)	47 (37%)
SD ≤ 1.5	1	1	1	1
SD > 1.5	54	41	68	46
NPV	98%	98%	99%	98%
Moderate risk: n (%)	65 (52%)	83 (65%)	51 (41%)	70 (55%)
SD ≤ 1.5	10	19	13	8
SD > 1.5	55	64	38	62
PPV	N/A	N/A	N/A	N/A
High risk: n (%)	7 (6%)	2 (2%)	5 (4%)	10 (8%)
SD ≤ 1.5	4	1	2	9
SD > 1.5	3	1	3	1
PPV	57%	50%	40%	90%