Fig. 2.

a Browser view of AHRR SM-DMR with genomic sequence for 4 CpGs measured by pyrosequencing that displays smoking-associated hypomethylation. The red vertical bars indicate percent hypomethylation at CpGs in this AHRR DMR region that are associated with smoking in adults [7]. The CpG at chr5:373378 is referred to as cg05575921 on Illumina 450K and 850K arrays. b–d Pyrosequencing measurements of 4 AHRR CpGs (mean, +/− SEM) for prenatal smoke exposure and nonsmokers measured in DNA from b whole cord blood, c CD14+ monocytes, and d CD235a+ nRBCs