. 2019 Jun 10;19:508. doi: 10.1186/s12879-019-4093-1

Table 5.

MIC distribution of Eravacycline and relevant antibiotics against Staphylococcus. spp of different resistance characteristics

Antibiotics		MRSA^a, N = 15		MSSA^b, N = 6			MRCoNS^c, N = 24				MSCoNS^d, N = 15
	MIC₅₀	MIC₉₀	Range	MIC₅₀	MIC₉₀	Range	MIC₅₀	MIC₉₀		Range	MIC₅₀	MIC₉₀	Range
Eravacycline		0.25	0.5	0.032–1	0.064	0.5	0.016–2	0.25	1	0.016–2	0.016	0.25	0.008–0.25
Tigecycline		0.25	0.5	0.125–0.5	0.25	0.25	0.125–0.25	0.25	0.5	0.125–0.5	0.125	0.25	0.064–0.25
Oxacillin		64	64	2–64	0.25	0.5	0.25–0.5	2	64	0.5–256	0.125	0.25	0.125–0.25
Cefoxitin		256	256	32–256	4	4	2–4	16	256	2–256	2	8	1–8
Vancomycin		1	1	0.5–1	0.5	0.5	0.5–0.5	1	2	0.5–2	0.5	1	0.25–1
Teicoplanin		2	2	0.5–2	0.5	0.5	0.5–1	2	4	0.064–8	0.5	2	0.125–2
Erythromycin		256	256	0.25–256	256	256	0.25–256	64	256	0.125–256	0.25	256	0.064–256
Minocycline		4	16	0.064–32	0.064	0.125	0.064–0.125	0.25	0.5	0.064–8	0.125	0.25	0.064–0.5
Ciprofloxacin		64	64	0.25–64	0.5	0.5	0.25–0.5	16	64	0.125–64	0.25	8	0.125–64
Levofloxacin		32	64	0.25–64	0.25	0.25	0.125–0.5	4	128	0.25–128	0.25	0.5	0.125–128
Moxifloxacin		8	16	0.016–32	0.032	0.064	0.016–0.064	1	16	0.064–32	0.064	1	0.032–16
Trimethoprim/Sulfamethoxazole		0.125	16	0.032–16	0.032	0.064	0.032–0.25	4	32	0.064–64	0.125	4	0.016–4
Chloramphenicol		8	8	4–32	8	8	4–64	4	8	2–64	4	4	2–8
Rifampin		256	256	0.004–256	0.008	0.016	0.004–0.016	0.008	256	0.004–256	0.008	0.016	0.004–0.016
Clindamycin		128	256	0.064–256	0.064	256	0.064–256	0.125	256	0.064–256	0.064	0.125	0.064–0.25
Linezolid		1	2	0.5–2	1	2	1–2	1	1	0.5–1	1	1	0.5–2

^a Methicillin-resistant Staphylococcus aureus. ^b Methicillin- sensitive Staphylococcus aureus

^c Methicillin-resistant coagulase-negative staphylococci. ^d Methicillin- sensitive coagulase-negative staphylococci