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. 2019 Jun 10;19:508. doi: 10.1186/s12879-019-4093-1

Table 6.

MIC distribution of Eravacycline and relevant antibiotics against Enterococci. spp of different resistance characteristics

Antibiotics E.faecalis, n = 10 E.faecium, n = 8 VREa, n = 3
MIC50 MIC90 Range MIC50 MIC90 Range MIC50 MIC90 Range
Eravacycline 0.032 0.032 0.016–0.125 0.016 0.032 0.008–0.064 0.016 0.032 0.008–0.032
Tigecycline 0.064 0.064 0.064–0.125 0.064 0.064 0.016–0.125 0.125 0.25 0.125–0.25
Ampicillin 1 8 1–8 64 64 4–64 64 64 64–64
Vancomycin 1 2 0.5–2 0.5 1 0.25–1 128 128 128–128
Teicoplanin 0.125 0.25 0.032–0.25 0.25 0.25 0.064–0.25 32 64 32–64
Erythromycin 1 256 0.25–256 256 256 0.016–256 0.125 256 0.125–256
Minocycline 16 16 0.064–16 0.032 16 0.032–16 0.064 16 0.064–16
Ciprofloxacin 2 32 0.5–64 64 64 4–64 64 64 64–64
Levofloxacin 2 64 1–64 64 128 1–128 64 64 64–64
Linezolid 1 2 1–2 1 1 0.5–1 1 1 1–1

a VRE referred to vancomycin-resistant Enterococci. All of the 3 VRE strains in this study were E.faecium