Table 1.
Demographic information and summary statistics for age, IQ and psychopathology symptoms
| 22q11.2DS | Controls | |||||||
|---|---|---|---|---|---|---|---|---|
| n | Mean (range) | SD | n | Mean (range) | SD | t | p | |
| Age | 54 | 13.73 (6.45-18.56) | 3.44 | 24 | 12.99 (8.50–16.95) | 2.52 | 1.06 | .292 |
| FSIQ | 54 | 72.06 (51–105) | 13.13 | 24 | 108.25 (63–139) | 18.16 | − 8.79 | < .001 |
| n | Median | IQR | n | Median | IQR | W | p | |
| ADHD symptoms | 54 | 3 | 7.75 | 24 | 0 | 0.00 | 1761 | < .001 |
| Indicative ASD symptoms | 53 | 9 | 9.00 | 23 | 1 | 3.00 | 2545 | < .001 |
| anxiety symptoms | 54 | 1 | 6.00 | 24 | 0 | 2.00 | 1198 | .039 |
| Mother’s ethnic background | n (families) | % | ||||||
| Caucasian | 54 | 93.1 | ||||||
| Other | 4 | 6.9 | ||||||
| Mother’s education level | n | % | ||||||
| High (University degree and/or other postgraduate qualification) | 12 | 20.7 | ||||||
| Low (O-levels, GCSE’s) | 10 | 17.2 | ||||||
| Middle (A-level’s, highers, vocational training) | 29 | 50.0 | ||||||
| No school leaving exams | 4 | 6.9 | ||||||
| Unknown | 3 | 5.2 | ||||||
| Approximate family income | n (families) | % | ||||||
| <=£19,999 | 8 | 13.8 | ||||||
| £20,000–£39,999 | 14 | 24.1 | ||||||
| £40,000–£59,999 | 16 | 27.6 | ||||||
| £60,000+ | 14 | 24.1 | ||||||
| Unknown | 6 | 10.3 | ||||||
Note: 148 families took part, and 4 families provided only a sibling control
FSIQ full-scale IQ, ADHD attention deficit hyperactivity disorder, ASD autism spectrum disorder, 22q11.2DS 22q11.2 deletion syndrome