Table 3.
Lung cancer incidence per 10,000 person-years by sex and age in patients with connective tissue disease-associated interstitial lung disease (CTD-ILD) and interstitial lung disease (ILD)-only
| Men | Women | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age (years) | Incidence CTD-ILD | Incidence ILD Only | RR | 95% CI | P value | E value | Incidence CTD-ILD | Incidence ILD Only | RR | 95% CI | P value | E value |
| 40–49 | 161.7 | 48.8 | 3.23 | 1.11–9.39 | 0.03 | 5.91 (1.45-NA) | 77.2 | 41.2 | 1.91 | 0.63–5.81 | 0.25 | |
| 50–59 | 201.8 | 107.2 | 1.83 | 0.97–3.46 | 0.06 | 119.3 | 40.8 | 2.81 | 1.23–6.42 | 0.01 | 5.06 (1.76-NA) | |
| 60–69 | 294.2 | 286.4 | 1.02 | 0.67–1.54 | 0.90 | 152.2 | 83.1 | 1.78 | 0.99–3.18 | 0.05 | ||
| 70–79 | 352.3 | 288.8 | 1.20 | 0.75–1.93 | 0.43 | 170.6 | 129.1 | 1.31 | 0.74–2.32 | 0.35 | ||
| ≥ 80 | 414.3 | 424.9 | 1.00 | 0.36–2.77 | 0.99 | 114.4 | 318.0 | 0.43 | 0.10–1.78 | 0.24 | ||
| Total | 269.4 | 209.9 | 1.27 | 0.98–1.65 | 0.06 | 127.0 | 103.7 | 1.28 | 0.95–1.73 | 0.09 | ||
RR Rate ratio, CI confidence interval, NA not available, E value was calculated by VanderWeele and Ding method [29]