Table 6.
All-cause mortality per 10,000 person-years by age in patients with connective tissue disease-associated interstitial lung disease (CTD-ILD) and interstitial lung disease (ILD)-only in women
| Age (years) | CTD-ILD | ILD-only | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Population (n) | Deaths (n) | Person-years of follow-up | Mortality | Population (n) | Deaths (n) | Person-years of follow-up | Mortality | RR | 95% CI | P value | E value | |
| 40–49 | 382 | 14 | 1759.9 | 79.5 | 665 | 16 | 2952.5 | 54.2 | 1.46 | 0.66–3.20 | 0.38 | |
| 50–59 | 515 | 39 | 2289.4 | 170.4 | 1120 | 42 | 4980.1 | 84.3 | 2.01 | 1.27–3.20 | < 0.01 | 3.43 (1.85-NA) |
| 60–69 | 499 | 71 | 2154.8 | 329.5 | 1516 | 120 | 6602.2 | 181.8 | 1.81 | 1.33–2.45 | < 0.01 | 3.02 (1.99-NA) |
| 70–79 | 321 | 87 | 1304.2 | 667.1 | 1651 | 313 | 6766.0 | 462.6 | 1.44 | 1.12–1.83 | < 0.01 | 2.23 (1.48-NA) |
| > 80 | 53 | 20 | 197.2 | 1014.2 | 866 | 258 | 3295.2 | 783.0 | 1.29 | 0.77–2.04 | 0.32 | |
| total | 1770 | 231 | 7705.7 | 299.8 | 5818 | 749 | 24,596.3 | 304.5 | 0.98 | 0.84–1.14 | 0.86 | |
RR Rate ratio, CI, confidence interval, NA not available, E value was calculated by VanderWeele and Ding method [29]