Table 1.
Measures, methods and assessment points used in the study
| Variable | Measure | Method | T0 Baseline |
T1 12 weeks |
T2 1 year |
|---|---|---|---|---|---|
| Psychiatric diagnosis | M.I.N.I. | Interview | X | X | X |
| Anxiety symptoms | BAI | Self-report | X | X | X |
| Depression symptoms | MADRS | Self-report | X | X | X |
| Psychoactive drugs | Questionnaire | Self-report | X | X | X |
| Blood pressure | MmHg | Objective assessment | X | X | X |
| BMI | Kg/m2 | Objective assessment | X | X | X |
| Alcohol use | AUDIT | Self-report | X | X | X |
| Quality of life | EQ-5D | Self-report | X | X | X |
| Cognitive function | WAIS-IV (d.s., b.d., m.r.) | Objective assessment | X | X | X |
| Cognitive function | D-KEFS (d.f.) | Objective assessment | X | X | X |
| Cardiovascular fitness | Åstrand’s ergometer test | Objective assessment | X | X | X |
| Muscle strength | One-leg-rising-test | Objective assessment | X | X | X |
| Sick leave | Questionnaire | Self-report | X | X | X |
| Hormones/cytokines | S-IGF-1, S-BDNF, S-VEGF, CRP | Blood samples | X | X | X |
M.I.N.I. Mini International Neuropsychiatric Interview, BAI Beck Anxiety Inventory, MADRS Montgomery Åsberg Depression Rating Scale, BMI Body mass index, AUDIT Alcohol Use Disorders Identification Test, EQ-5D EuroQoL-5 Dimension Questionnaire, WAIS-IV Wechsler Adult Intelligence Scale, 4th edition, d.s. digit span, b.d. block design, m.r. matrix reasoning, D-KEFS Delis-Kaplan Executive Function System, d.f. design fluency, S-IGF-1 serum insulin-like growth factor 1, S-BDNF serum brain-derived neurotrophic factor, S-VEGF serum vascular endothelial growth factor, CRP high sensitivity C-reactive protein