Table 2.
Association of Breastfeeding Patterns with Epithelial Ovarian Cancer, the HOPE Study 2003–2008
| Controls | Cases | Odds Ratio |
95% Confidence Interval |
Adjusted Odds Ratio* |
95% Confidence Interval |
|
|---|---|---|---|---|---|---|
| Factor | N (%) | N (%) | ||||
| Ever Breastfed | ||||||
| No | 684 (43.5) | 386(56.0) | 1 | 1 | ||
| Yes | 888 (56.5) | 303(44.0) | 0.6 | 0.50–0.72 | 0.70 | 0.58–0.85 |
| Breastfed All Offspring | ||||||
| Never Breastfed | 684 (43.5) | 386(56.0) | 1 | 1 | ||
| Breastfed some, but not all | 328 (20.9) | 119(17.3) | 0.64 | 0.50–0.82 | 069 | 0.53–0.89 |
| Breastfed All | 560 (35.6) | 184(26.7) | 0.58 | 0.47–0.72 | 0.71 | 0.57–0.89 |
| Breastfed First Offspring | ||||||
| Never Breastfed | 684 (43.5) | 386(56.0) | 1 | 1 | ||
| Breastfed some, but not first | 122 (7.8) | 46(6.7) | 0.67 | 0.47–0.96 | 0.77 | 0.52–1.11 |
| Breastfed First Offspring | 766 (48.7) | 257(37.3) | 0.59 | 0.49–0.72 | 0.69 | 0.57–0.85 |
| Breastfed Last Offspring | ||||||
| Never Breastfed | 684 (43.5) | 386(56.0) | 1 | 1 | ||
| Breastfed some, but not last | 198 (12.6) | 71 (10.3) | 0.64 | 0.47–0.86 | 0.65 | 0.47–0.89 |
| Breastfed Last | 690 (43.9) | 232(33.7) | 0.60 | 0.49–0.72 | 0.72 | 0.58–0.89 |
| Number of Breastfeeding Episodes | ||||||
| Never Breastfed | 684 (43.5) | 386(56.0) | 1 | 1 | ||
| 1 or 2 episodes | 619 (39.4) | 238(34.5) | 0.68 | 0.56–0.83 | 0.78 | 0.64–0.96 |
| 3 or more episodes | 269 (17.1) | 65(9.4) | 0.43 | 0.32–0.58 | 0.49 | 0.36–0.68 |
| trend p=0.01 | ||||||
*
Separate models and analyses for each factor. Each model adjusted for age, race, education, duration of oral contraceptive use, and number of pregnancies.