Table 3.
Association of Breastfeeding Duration with Epithelial Ovarian Cancer, the HOPE Study 2003–2008
| Factor | Controls | Cases | Odds Ratio |
95% Confidence Interval |
Adjusted Odds Ratio* |
95% Confidence Interval |
|---|---|---|---|---|---|---|
| N (%) | N (%) | |||||
| Total Duration of Breastfeeding (years) | ||||||
| Never Breastfed | 684 (43.5) | 386 (56.0) | 1 | 1 | ||
| <1 | 502 (31.9) | 192 (27.9) | 0.68 | 0.55–0.83 | 0.75 | 0.61–0.94 |
| 1 or more | 386 (24.6) | 110(16.0) | 0.50 | 0.39–0.65 | 0.62 | 0.47–0.80 |
| Duration of Breastfeeding per breastfeeding episode (months) | ||||||
| Never Breastfed | 684 (43.5) | 386 (56.0) | 1 | 1 | ||
| ≤3 | 375 (23.9) | 143 (20.8) | 0.68 | 0.54–0.85 | 0.73 | 0.58–0.93 |
| 4 or more | 513 (32.6) | 159 (23.1) | 0.55 | 0.44–0.60 | 0.67 | 0.53–0.85 |
| Duration of breastfeeding first breastfeeding episode (months) | ||||||
| Never Breastfed | 684 (43.5) | 386 (56.0) | 1 | 1 | ||
| ≤3 | 396 (25.2) | 151 (21.9) | 0.68 | 0.54–0.85 | 0.75 | 0.59–0.94 |
| 4 or more | 492 (31.3) | 151 (21.9) | 0.54 | 0.44–0.68 | 0.66 | 0.52–0.84 |
| Duration of breastfeeding last breastfeeding episode (months) | ||||||
| Never Breastfed | 684 (43.5) | 386 (56.0) | 1 | 1 | ||
| ≤3 | 393 (25.0) | 154 (22.4) | 0.69 | 0.55–0.87 | 0.75 | 0.60–0.95 |
| 4 or more | 495 (31.5) | 148 (21.5) | 0.53 | 0.42–0.66 | 0.65 | 0.51–0.83 |
*
Separate models and analyses for each factor. Each model adjusted for age, race, education, duration of oral contraceptive use, and number of pregnancies.