Table 4.
Associations of adiposity trajectories through adolescence with PWV
|
Univariate analysis (n=3417)* |
Multivariable adjusted analysis (n=1940)† |
|||
|---|---|---|---|---|
| PWV coefficient, m/s (95% CI) | p value | PWV coefficient, m/s (95% CI) | p value | |
| Total FMI (kg/m2) | ||||
| Low trajectory | −0·00 (−0·06 to 0·05) | 0·95 | 0·02 (−0·06 to 0·09) | 0·65 |
| High trajectory | 0·07 (0·01 to 0·14) | 0·027 | 0·15 (0·05 to 0·24) | 0·0044 |
| Trunk FMI (kg/m2) | ||||
| Low trajectory | −0·03 (−0·08 to 0·02) | 0·27 | −0·03 (−0·10 to 0·04) | 0·41 |
| High trajectory | 0·10 (0·03 to 0·17) | 0·0041 | 0·15 (0·06 to 0·25) | 0·0021 |
| BMI trajectories (kg/m2) | ||||
| Low trajectory | 0·01 (−0·04 to 0·06) | 0·59 | −0·05 (−0·11 to 0·02) | 0·18 |
| High trajectory | 0·09 (0·03 to 0·16) | 0·0030 | 0·04 (−0·04 to 0·13) | 0·34 |
In each case, the middle trajectory is the reference group. PWV=pulse wave velocity. LDL=low density lipoprotein. FMI=fat mass indexed to squared height. BMI=body-mass index.
*
Adjusted for sex.
†
Adjusted for sex, systolic blood pressure, LDL, C-reactive protein, socioeconomic status, Z-score of BMI at 17 years (except for models incorporating trajectories of BMI), and birthweight.