Figure 3.
miR-6716-5p level was correlated with liver metastasis and survival of CRC patients. (A) Kaplan–Meier analysis for overall survival (OS) rate between miR-6716-5p high-expression group and miR-6716-5p low-expression group in CRC patients. (B) Relative miR-6716-5p level was analyzed between non-metastatic CRC (NMCRC) patients and CRC with liver metastasis (CRLM) patients. (C) Kaplan–Meier analysis for OS rate between miR-6716-5p high group and miR-6716-5p low group in CRLM patients. (D) Relative NAT10 mRNA expression was analyzed between miR-6716-5p high group and miR-6716-5p low group. (E) Correlation between miR-6716-5p level and NAT10 mRNA level was calculated according to Spearman’s rank correlation coefficient in CRC specimen (n=80). CRLM represents CRC with liver metastasis. NMCRC represents non-metastatic CRC. (B, D) The Mann–Whitney U test was used to compare the levels of NAT10 mRNA or miR-6716-5p between groups and horizontal line was the mean value in two groups, respectively.