Table 1.
Variable | PD-RBD | PD-nRBD | Controls | P |
---|---|---|---|---|
Age, y | 66.7 (7.6) | 63.1 (8.9) | 63.3 (8.1) | 0.36* |
Men, n (%) | 10 (67) | 5 (33) | 25 (61) | 0.14† |
Education, y | 14.2 (3.6) | 15.7 (3.9) | 14.6 (4.1) | 0.56* |
PD duration, diagnosis, y | 3.9 (2.9) | 3.7 (2.6) | – | 0.85‡ |
% tonic REM sleep motor activity | 56.3 (33.8) | 23.0 (32.5) | – | 0.01 § |
% phasic REM sleep motor activity | 38.6 (17.3) | 19.8 (16.9) | – | 0.004 § |
UPDRS-III, total “ON” state | 24.1 (10.0) | 17.6 (8.5) | – | 0.08‡ |
Levodopa equivalent dosage, mg | 625.2 (347.1) | 447.8 (171.5) | – | 0.65§ |
Levodopa use, % | 87 | 93 | – | 0.54|| |
Dopamine agonist use, % | 47 | 40 | – | 0.71|| |
MCI, % | 53 | 27 | – | 0.14|| |
Data are presented as mean (SD). Bold values represent significant between-group differences.
MCI = mild cognitive impairment; PD-RBD = Parkinson’s disease with REM sleep behavior disorder; PD-nRBD = PD without RBD; UPDRS-III = Unified Parkinson’s Disease Rating Scale, Part III.
*Analysis of variance.
†Fisher–Freeman–Halton exact test for contingency.
‡Student’s t-test.
§Mann–Whitney U test.
||Chi-squared test.