Table 1.
Characteristics of the HIV-Infected Patient Cohort Overall and by TB Status
| Demographics | N = 131 (%) | Pulmonary TB Detected (n = 15) | No Pulmonary TB (n = 116) | P |
|---|---|---|---|---|
| Males | 92 (70) | 11 (73) | 81 (70) | .78 |
| Mean age in years (SD) | 42 (10) | 42 (10) | 44 (12) | .56 |
| Mean BMI [kg/m2] (SD) | 22 (2.6) | 21.4 (3.3) | 22.6 (2.5) | .22 |
| Unemployed | 86 (66) | 13 (87) | 73 (63) | .07 |
| Prison history | 21 (16) | 3 (20) | 18 (16) | .66 |
| Current tobacco use | 76 (58) | 10 (67) | 66 (57) | .47 |
| Alcohol use | 55 (42) | 6 (40) | 49 (42) | .87 |
| Injection drug use | 52 (40) | 10 (67) | 42 (36) | .02 |
| Hepatitis C virus antibody positive | 60 (46) | 11 (73) | 49 (42) | .02 |
| Prior TB treatment for active TB | 4 (3) | 0 | 4 (4) | .47 |
| HIV | ||||
| Mean CD4 (SD) | 174 (184) | 133 (146) | 179 (188) | .28 |
| Median CD4 (IQR) | 122 (24–282) | 79 (33–198) | 123 (21–295) | .61 |
| Presenting opportunistic infections | ||||
| Oral thrush | 34 (26) | 9 (60) | 25 (22) | <.01 |
| Cryptococcemia | 12 (9) | 2 (13) | 10 (9) | .55 |
| PCP pneumonia | 11 (8) | 0 | 11 (10) | .36 |
| Bacterial pneumonia | 38 (29) | 7 (47) | 31 (27) | .11 |
| Symptoms at study enrollment | ||||
| Cough | 37 (28) | 9 (60) | 28 (24) | <.01 |
| Shortness of breath | 15 (12) | 3 (20) | 12 (10) | .27 |
| Night sweats | 34 (26) | 8 (53) | 26 (22) | .01 |
| Weight loss | 57 (44) | 11 (73) | 46 (40) | .01 |
| Fever | 75 (57) | 12 (80) | 63 (54) | .01 |
| Temperature ≥ 38.0○C | 64 (49) | 12 (80) | 52 (45) | .01 |
| ≥1 symptom | 83 (63) | 14 (93) | 69 (60) | .01 |
BMI indicates body mass index; HIV, human immunodeficiency virus; IQR, interquartile range; PCP, pneumocystis pneumonia; SD, standard deviation; TB, tuberculosis.