Table 1.

Demographic and Clinical Characteristics of Severe Fever With Thrombocytopenia Syndrome Cluster in Dongtai County

	Case Patient
Characteristics	Index/A	B	C	D
General
Sex	Male	Female	Male	Male
Age, y	70	69	65	46
Occupation	Retired cadre worker	Housewife	Folk mortician	Village doctor
Medical history	Hypertension, thyroidectomy	No relevant history	Hypertension	Hepatitis B, diabetes
Relationship with index case patient (case patient A)	Self	Spouse	Prepared body for burial (dressed and placed in coffin)	Provided medical service
Date of illness onset	10 July 2015	26 July 2015	26 July 2015	31 July 2015
Date of hospitalization	12 July 2015	29 July 2015	4 August 2015	4 August 2015
Clinical symptoms
Fever, maximum body temperature, °C	38.8	39.6	39.0	40.0
Chills	Yes	Yes	Yes	No
Headache	Yes	Yes	Yes	No
Muscular stiffness	Yes	Yes	Yes	Yes
Low back pain	Yes	No	Yes	No
Fatigue	Yes	Yes	Yes	Yes
Anoxia	Yes	Yes	Yes	Yes
Nausea	Yes	Yes	No	No
Vomiting	Yes	Yes	Yes	No
Abdominal pain and/or distension	No	No	Yes	No
Diarrhea	Yes	Yes	No	No
Neurological symptoms	Yes	Yes	No	No
Skin petechiae	Yes	No	No	No
Superficial lymphadenopathy	No	No	No	No
Hematemesis	Yes	No	No	No
Hematuria	Yes	Yes	No	No
Hematochezia	Yes	Yes	No	No
Laboratory findings
Cell count, ×109/L
WBCs	3.21	1.00	1.74	1.07
Lymphocytes	0.80	0.41	0.66	0.42
Platelets	44	96	89	88
ALT, U/L	138	41	20	202
AST, U/L	1154	86	35	219
Prothrombin time, s	19.1	Not tested	11.9	13.4
aPTT, s	106.8	Not tested	37.7	46.9
Urine protein	Not tested	Not tested	1+	2+

Abbreviations: ALT, alanine aminotransferase; aPTT, activated partial thromboplastin time; AST, aspartate aminotransferase; WBCs, white blood cells, 1+, urinary protein concentration of 0.2-1.0g/L; 2+, urinary protein concentration of 1.0-2.0g/L.