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. 2019 May 10;44(1):47–56. doi: 10.3892/ijmm.2019.4194

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Downregulation of miRNA-302a regulates RelA/BRD4/NF-κB signaling pathway in an in vitro model of infantile pneumonia. (A) miRNA-302a matches to the sequence in the 3-UTR of RelA, (B) luciferase reporter, (C) RelA, (D) BRD4 and (E) NF-κB protein expression by statistical analysis, and (F) western blotting analysis, (G) RelA protein expression by immunofluorescence. ^**P<0.01 vs. the negative control group. Negative, negative control group; anti-302a, downregulation of miRNA-302a group; NF, nuclear factor; BRD4, bromodomain-containing protein 4; miRNA, microRNA.