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. 2019 May 10;44(1):47–56. doi: 10.3892/ijmm.2019.4194

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Si-BRD4 reduces the effects of miRNA-302e on inflammation in an in vitro model of infantile pneumonia. (A) BRD4 and (B) NF-κB protein expression by statistical analysis and (C) western blotting analysis, (D) TNF-α, (E) IL-1β, (F) IL-6 and (G) IL-18. ^**P<0.01 vs. the negative control group; ^##P<0.01 vs. the downregulation of miRNA-302e group. Negative, negative control group; anti-302e, downregulation of miRNA-302e group; anti-302e+si-BRD4, Si-BRD4 and downregulation of miRNA-302a group; TNF, tumor necrosis factor; IL, interleukin; NF, nuclear factor; BRD4, bromodomain-containing protein 4; miRNA, microRNA; si, small interfering.