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. 2019 May 13;44(1):240–252. doi: 10.3892/ijmm.2019.4196

Figure 1.

Figure 1

Fold-change in expression of miR-490-5p relative to the internal control gene (U6) in laryngeal tumor, tumor-adjacent tissues and tumor cell lines as well as the overall survival curves of pharyngolaryngeal cancer with different expression levels of miR-490-5p and the alteration of cell viabilities in control, NC and miR-490-5p mimics groups of BICR 18 and FaDu cells. (A) Relative miR-490-5p expression in laryngeal tumor and tumor-adjacent tissues. (B) The overall survival curves of pharyngolaryngeal cancer with low or high expression level of miR-490-5p. (C) Relative miR-490-5p expression in Detroit 562, HNE-3, FaDu, BICR 18, HaCaT and NP 69 cell lines. (D) Relative miR-490-5p expression in each group of BICR 18 cells. (E) Cell viability of BICR 18 cells in each group following 24 and 48 h of culturing since the transfection. (F) Relative miR-490-5p expression in each group of FaDu cells. (G) Cell viability of FaDu cells in each group following 24 and 48 h of culturing since the transfection. Bars indicated the mean ± standard deviation. *P<0.05 vs. NP69 cells; #P<0.05 vs. HaCaT cells; ^P<0.05 vs. NC groups. NC, negative control; miR, microRNA.