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. 2019 Jun 4;10:1237. doi: 10.3389/fimmu.2019.01237

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Copyright © 2019 Soto-Dávila, Hossain, Chakraborty, Rise and Santander.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transmission electron microscopy of Atlantic cod macrophages infected with A. salmonicida. (a,b) Mock infected Atlantic cod head kidney macrophages (control). (× 2,100, scale bar 1 μm). (c–e) Atlantic cod head kidney macrophages infected with A. salmonicida. (c and d: × 2700, scale bar 1 μm; e: × 2,100, scale bar 1 μm). (f,g) Intracellular A. salmonicida. (f: × 15,000, scale bar 200 nm; g: × 30,000, scale bar 100 nm). (h,i) Atlantic cod head kidney macrophages infected with the formalin killed A. salmonicida. (h: × 2,700, scale bar 1 μm; i: × 1,650, scale bar 2 μm). NU, Nucleus; PS, Pseudopodia; ER, Endoplasmic reticulum; MI, Mitochondria; AS, A. salmonicida; EV, Endoplasmic vesicles; OMV, Outer membrane vesicles (arrows); FK, Formalin killed A. salmonicida; SB, Secretion bodies; and AC, Apoptotic bodies.