Table 9. The resistance and sensitivity of TKI drugs based on a mutation profile in the chronic myeloid leukemia patients.

«-» resistance, «+» - sensitivity

TKI, tyrosine kinase inhibitor

Drug Mutation profile	Nilotinib	Dasatinib	Ponatinib	Bosutinib
T315I	-	-	+	-
T315A	+	-	+	+
Y253H E255K/V F359C/V/C/I	-	+	+	+
V299L	+	-	+	-
F317L/V/I/C	+	-	+	+