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. 2019 Jun 6;14:4145–4155. doi: 10.2147/IJN.S202466

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© 2019 Pei et al.

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Fullerol decreases protein levels of TLR4 (A) and p-P38 (C) in the cytosol fraction and NFkB (B) and FoxO1 (D) in the nuclear fraction determined by western blot. Cells were treated by 100 ng/mL LPS alone (LPS) or 100 ng/mL LPS together with 1 µM fullerol (LPS + FUL). It was shown that protein levels of these signal molecules were significantly lower in LPS group than in LPS + FUL group. *P<0.05, n=3.

Abbreviations: FUL, fullerol; FoxO1, forkhead box transcription factor 1; LPS, lipopolysaccharide; NFkB, nuclear factor-kappaB; TLR, toll-like receptor.