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. 2019 Jun 6;14:4145–4155. doi: 10.2147/IJN.S202466

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© 2019 Pei et al.

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Representative H&E staining of synovium from rat knee joints (control: PBS, injured: MIA) with (FUL) or without (NT) fullerol treatment for 5 days.

Notes: Fullerol of 2 mg/kg weight was administered intravenously immediately after MIA injection. The results showed that fullerol reduces red blood cells (blue arrows) and fibroblast-like cells (black arrows) in the synovium of the injured knee seen in the up/left image of the MIA/NT group.

Abbreviations: FUL, fullerol; MIA, monoiodoacetate; NT, no treatment.