Table 2.

Sex Differences in Comorbid Disease Burden in Incident Parkinson Disease Cohort

	Cumulative Incidence of CCW condition (2002–2008) (per 100 PD patient years) adjusted for race (95%CI)				IRR (95%) (women vs men) adjusted for race	p-value
Comorbid Disease
	N	Men	N	Women
Atrial Fibrillation	7,472	3.46 (3.27–3.65)	7,597	2.78 (2.63–2.93)	0.8 (0.78–0.83)	<.0001
Dementia	18,612	16.34 (15.8–16.89)	19,058	15.68 (15.17–16.2)	0.96 (0.94–0.98)	<.0001
Myocardial Infarction	3,908	1.76 (1.63–1.89)	3,650	1.33 (1.23–1.43)	0.75 (0.72–0.79)	<.0001
Cataract	8,059	11.77 (11.17–12.41)	7,506	10.91 (10.35–11.5)	0.93 (0.9–0.96)	<.0001
Congestive Heart Failure	14,956	12.75 (12.3–13.22)	15,694	11.7 (11.28–12.13)	0.92 (0.9–0.94)	<.0001
Colorectal Cancer	992	0.46 (0.4–0.53)	945	0.36 (0.31–0.42)	0.78 (0.71–0.85)	<.0001
COPD	10,018	6.73 (6.43–7.03)	9,944	5.23 (5–5.46)	0.78 (0.76–0.8)	<.0001
Depression	12,122	7.36 (7.06–7.68)	13,448	9.43 (9.04–9.83)	1.28 (1.25–1.31)	<.0001
Diabetes	7,025	7.17 (6.85–7.51)	8,264	6.92 (6.61–7.24)	0.97 (0.93–1)	0.0283
Glaucoma	3,340	2.44 (2.29–2.61)	3,855	2.37 (2.22–2.52)	0.97 (0.93–1.02)	0.1929
Hip Fracture	4,422	1.28 (1.19–1.38)	7,390	1.92 (1.79–2.07)	1.51 (1.45–1.56)	<.0001
Ischemic Heart Disease	9,641	14.76 (14.12–15.43)	11,358	12.37 (11.84–12.93)	0.84 (0.82–0.86)	<.0001
Chronic Kidney Disease	14,640	9.23 (8.91–9.57)	13,640	6.75 (6.51–7)	0.73 (0.71–0.75)	<.0001
Lung Cancer	1,291	0.53 (0.47–0.61)	928	0.32 (0.27–0.36)	0.59 (0.54–0.64)	<.0001
Osteoporosis	6,347	3.33 (3.18–3.5)	11,548	10.03 (9.59–10.48)	3.01 (2.92–3.1)	<.0001
Arthritis	9,431	7.64 (7.31–7.99)	11,373	11.23 (10.75–11.73)	1.47 (1.43–1.51)	<.0001
Stroke/TIA	10,893	8.32 (7.99–8.66)	12,355	7.89 (7.59–8.21)	0.95 (0.92–0.97)	<.0001