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. 2019 Apr 30;62(7):1173–1184. doi: 10.1007/s00125-019-4874-5

Table 7.

 Multivariate ORs with 95% CIs, adjusted for confounders

Model and confounders Risk factor OR (95% CI) p value
Model 1 (maternal UTI, PROM, maternal age, preterm deliverya) Caesarean section 1.08 (1.02, 1.15) <0.01
Model 2 (maternal UTI, PROM, maternal age) Very pretermb 0.54 (0.38, 0.76) <0.001
Moderate to late pretermc 1.24 (1.14, 1.35) <0.001
Model 3 (maternal UTI, PROM, maternal age, preterm deliverya) Birthweight z score 1.08 (1.06, 1.10) <0.001
Model 4 (maternal age) UTI 1.39 (1.04, 1.86) 0.025
Model 5 (maternal age) PROM 1.08 (1.01, 1.16) 0.023

The confounders are variables that introduced spurious associations through backdoor paths in the directed acyclic graph shown in Fig. 2

aGestational age at birth <259 days, bgestational age at birth <224 days, cgestational age at birth 224–258 days; full term ≥259 days is used as reference