Table 1.
Properties of 32 genetic loci identified in a GWAS on the EURO training data set
| Locus | SNP | a | A | p-value | MAF | #SNPs | Class. Mod. |
|---|---|---|---|---|---|---|---|
| 1p32.2 | rs2404983 | G | A | 3.06E-08 | 0.076 | 6 | D |
| 1p32.1 | rs4916071 | A | G | 2.06E-16 | 0.482 | 172 | D, R |
| 1p12 | rs200100774 | A | G | 1.39E-10 | 0.165 | 126 | D |
| 1p12 | rs61808932 | C | T | 5.92E-22 | 0.245 | 166 | D, R |
| 1q31.3 | rs949977 | G | C | 2.36E-09 | 0.314 | 58 | D |
| 1q31.3 | rs2821107 | T | A | 2.52E-22 | 0.209 | 287 | D, R |
| 2q31.1 | rs970797 | T | G | 4.58E-11 | 0.432 | 2 | D, R |
| 2q36.1 | rs1370926 | G | C | 1.61E-11 | 0.228 | 14 | D |
| 3q21.3 | rs2955084 | T | A | 3.68E-10 | 0.078 | 2 | D |
| 3q21.3 | rs2977562 | G | A | 1.80E-15 | 0.243 | 316 | D |
| 4q31.3 | rs10020603 | T | C | 4.45E-18 | 0.195 | 9 | D |
| 4q31.3 | rs17299889 | A | G | 4.67E-09 | 0.356 | 4 | D |
| 4q34.1 | rs1059045 | T | C | 7.23E-13 | 0.466 | 24 | D, R |
| 6p21.1 | rs227832 | C | T | 8.44E-14 | 0.257 | 214 | D, R |
| 6p21.1 | rs9395084 | C | T | 5.58E-09 | 0.407 | 118 | D |
| 6p21.1 | rs73735344 | A | G | 2.69E-12 | 0.153 | 112 | D |
| 6q23.2 | rs402020 | T | C | 5.20E-12 | 0.308 | 22 | D, R |
| 7p21.1 | rs1178103 | G | T | 8.24E-09 | 0.198 | 2 | D |
| 7q21.3 | rs10238953 | G | A | 1.48E-31 | 0.138 | 229 | D, R |
| 7q21.3 | rs2272224 | C | T | 1.17E-11 | 0.280 | 30 | D, R |
| 8p23.1 | rs2980419 | A | T | 5.11E-08 | 0.478 | 1 | D, R |
| 9p22.2 | rs13290470 | G | A | 2.53E-08 | 0.359 | 1 | D, R |
| 11p11.2 | rs150863859 | G | C | 4.50E-08 | 0.113 | 2 | D |
| 11q22.3 | rs7930466 | G | A | 5.80E-08 | 0.080 | 2 | D |
| 11q23.2 | rs7925936 | C | T | 8.38E-09 | 0.169 | 2 | D |
| 12q21.31 | rs7966105 | A | G | 8.18E-09 | 0.271 | 85 | D |
| 13q12.11 | rs2985662 | C | A | 5.40E-08 | 0.360 | 1 | D |
| 14q12 | rs143974562 | T | C | 3.10E-08 | 0.133 | 1 | D |
| 17q24.3 | rs72866756 | A | G | 3.21E-14 | 0.366 | 163 | D, R |
| 17q24.3 | rs11871949 | C | T | 4.63E-13 | 0.445 | 35 | D, R |
| 20p11.22 | rs2424392 | C | T | 5.85E-09 | 0.234 | 24 | D |
| 20p11.22 | rs6035946 | A | T | 1.53E-08 | 0.314 | 2 | D |
#SNPs number of SNPs reaching the FDRd p-value threshold (7.7 × 10E–8) within the same locus; Class. Mod. Classification model(s) deployed, can be dominant (D), recessive (R), or both (D, R) expressing the model of inheritance of each individual SNP used in the face-to-DNA classifiers
SNP single nucleotide polymorphism, peak SNP of the locus, a minor allele, A major allele, MAF minor allele frequency